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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FANCG All Species: 13.03
Human Site: T557 Identified Species: 31.85
UniProt: O15287 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15287 NP_004620.1 622 68554 T557 T Y F H L L Q T L K R L D R R
Chimpanzee Pan troglodytes XP_520551 622 68533 T557 T Y F H L L Q T L K R L D R R
Rhesus Macaque Macaca mulatta XP_001091966 622 68585 T557 T Y F H L L Q T L K R L D R R
Dog Lupus familis XP_854703 806 88753 T741 A S F H L L Q T L R K M D R R
Cat Felis silvestris
Mouse Mus musculus Q9EQR6 623 68487 L558 R D G S F Y L L Q T L K R L D
Rat Rattus norvegicus XP_001076851 623 68404 L558 R D G S F Y L L Q T L K R L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520423 598 65280 A529 P A L H L V R A L W K L N R R
Chicken Gallus gallus NP_989709 648 71724 V577 A A S Y L V Q V L W K L N R K
Frog Xenopus laevis NP_001098745 640 71329 H570 A A L T L V G H L I K L G R R
Zebra Danio Brachydanio rerio NP_991202 617 69657 L552 C K N T E M W L A E V L W R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.1 62.9 N.A. 72.5 71.7 N.A. 34.7 36.1 35.3 31 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 97.1 67.9 N.A. 81.5 81 N.A. 46.9 53 52 49.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 66.6 N.A. 0 0 N.A. 40 33.3 33.3 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 0 0 N.A. 66.6 66.6 46.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 30 0 0 0 0 0 10 10 0 0 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 0 0 0 0 0 0 0 0 40 0 20 % D
% Glu: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % E
% Phe: 0 0 40 0 20 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 20 0 0 0 10 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 50 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 30 40 20 0 0 10 % K
% Leu: 0 0 20 0 70 40 20 30 70 0 20 70 0 20 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 20 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 50 0 20 0 0 0 0 0 0 % Q
% Arg: 20 0 0 0 0 0 10 0 0 10 30 0 20 80 60 % R
% Ser: 0 10 10 20 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 30 0 0 20 0 0 0 40 0 20 0 0 0 0 0 % T
% Val: 0 0 0 0 0 30 0 10 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 20 0 0 10 0 0 % W
% Tyr: 0 30 0 10 0 20 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _